Research on extraction, enrichment and purification of some biologically active natural compounds

The study of the extraction, enrichment and purification of biologically active natural compounds is an important research area in the field of modern medicine and pharmaceuticals. Natural compounds can be extracted from a variety of sources, including plants, animals, bacteria, and fungi. Some important biologically active natural compounds include:

Alkaloids: Alkaloids are a class of organic compounds found in many plants and animals. Biologically active alkaloids such as morfin, codeine, quinine and caffeine are used medicinally to treat a variety of diseases.

Flavonoids: Flavonoids are a group of compounds with antioxidant and anti-inflammatory activity, found in many plants. Bioactive flavonoids such as quercetin, kaempferol and apigenin…

Terpenoids: Terpenoids are a group of biologically active compounds found in many plants and animals. The biologically active terpenoids such as carotenoids, limonene, pinene, etc.

Saponins: Saponins are compounds with antibacterial and anti-inflammatory activities found in many plants. Biologically active saponins such as ginsenoside and saikosaponin are used in medicine to support the treatment of a variety of diseases.

On the market today, most of the pharmaceutical materials are imported from abroad, most of which are from China. Vietnam is a country with diverse indigenous vegetation with many valuable medicinal sources, with many medicinal effects. After the harvest, most medicinal herbs are only dried, sliced, cooked in liquid, solid, dried form or extracted in the form of some raw active ingredients, which have not yet met the standards as raw materials for cosmetic pharmaceutical products. Products. These raw materials are often exported to other developed countries at low cost to enrich or refine bioactive compounds and then re-import at a relatively high price. Methods for the extraction, enrichment and purification of biologically active natural compounds include simple extraction, chromatography (thin layer chromatography (TLC), column chromatography (CC) and performance liquid chromatography (CC). high (HPLC), gas chromatography (GC)…) and purified. These methods help to separate biologically active compounds from natural sources and enrich them for use in medicine and pharmaceuticals.

Thus, the separation, enrichment of compounds or the purification of active substances from plant sources becomes a potential field, making the most of native plant resources, mastering medicinal materials, limiting dependence on imported sources, thereby improving the value of Vietnamese medicinal plants.